A55year old male with ? Nephrotic syndrome Known case of Hypertension since 10 daysAnemia under evaluation.
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CASE DISCUSSION:
•55 year old man, owns a restaurant at choutuppal presented with the complaints of
Bilateral lower limb swelling since 1 month
Reduced urine out since 20 days
Abdominal distension since 7 days
Scrotal swelling since 4 days
Patient used to previously work as a farmer and later in 2004 he and his wife started running their own restaurant at Choutuppal. He is a father of 2 children.
22 years back: He got diagnosed with pulmonary kochas for which he used ATT for 6 months
1 month back :
He first developed left lower limb swelling extending upto his ankle and he later gradually developed swelling of his right lower limb and the swelling in both his lower limbs extended upto his thighs
He even had difficulty in passing stools for which he received enema outside
Since 20 days - he has been experiencing reduced urine output
10 days back - When he paid a visit to a hospital with these complaints he got diagnosed to be hypertensive and was started on Tab Telma H in a local hospital and was also started on Tab Lasilactone 20/50
At this point his serum creatinine was 1.6 mg/dl
And his usg abdomen showed ascites and his kidney size was normal
Since 7 days - he even developed abdominal distension
Since 4 to 5 days he has also developed scrotal swelling
He however has no complaints of fever, cough, burning micturation, loose stools, vomiting
No complaints of dyspnea, hematuria, frothy urine, no complaints of Chest pain, palpitations, orthopnea, PND, bendopnia or trepopnea
On examination:
He has pallor with Grade 3 clubbing, that is parrot beak type
Bilateral pedal edema - of pitting type extending upto his thighs
JVP not elevated
HR of 75 bpm
Bp of 110/70mmhg
RR 20cpm
Spo2 maintaining at 99% at Room Air
GIT Examination:
Per Abdomen-
Abdomen distended with no scars, sinuses, engorged veins
No tenderness
Percussion-
Shifting dullness +
Bowel sounds +
Cvs Examination:
Apex beat + in 6th ICS at MCL
S1, S2+
Lungs:
Inspirstory crepts in bilateral all lung fields
Cns:
Normal
Provisional diagnosis:
? Nephrotic syndrome
Evaluation:
Hb - 9.4 g/dl
TLC - 5300
Plt - 1.84
CUE:
Albumin +++
Pus cells 4 to 6 cells
Albumin 2g/dl
Serum creatinine- 3.6mg/dl
Blood urea - 76 mg/dl
24 hours urinary protein shows a protein loss of 2,622 mg/dl
Usg abdomen shows normal sized Kidneys with grade 1 RPD changes along with moderate ascites
Diagnosis:
? Nephrotic syndrome
Known case of Hypertension since 10 days
Anemia under evaluation.
- Blood urea: 74 mg/dl.
- Serum creatinine: 3.6 mg/dl.
- Serum Albumin : 2.0 gm/dl.
- Serum proteins: 4.0 gm/ dl.
- Sodium: 132 m eq/ l.
- Potassium: 5.1 m eq/l.
- Chloride: 105 m eq/l.
- RBC : Normocytic Normochromic.
- WBC: with in normal limits with relative Eosinophilia.
- Platelets: Adequate.
- IMP: Normocytic Normochromic with relative Eosinophilia.
- Fluid Restriction <1.5 L/ day.
- Salt restriction <2 g/ day.
- Inj.Lasix 40 mg I.V / BD, if SBP is >>110 mmhg.
- Tab.Pan 40 mg PO/OD.
- Tab.ZOFER 4mg PO/SOS.
- Strict I/O charting.
- BP/PR/RR/SpO2 charting 4th hourly.
- Head end evaluation.
- INJ.Pantop 40 mg I.V/ OD.
- INJ.Lasix 40 mg I.V/BD.
- Adviced.
- Head end evaluation.
- Inj.Pan 40 mg I. V/ OD.
- Inj.Lasix 40 mg I. V/BD.
- Fluid Restriction <1L/ day and Salt restriction < 2 g/ day.
- Strict I/O charting.
- Monitor vitals.
- Tab.RAMIPRIL 2.5 mg/PO/OD.
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